A NEW CATEGORY OF SCREENING

Detecting
neurodegeneration
before it's diagnosed.

Parkinson's and Alzheimer's begin in the brain a decade or more before the first clinical symptom. The body emits a disease-related odor signature long before then — and we read it, using trained animal olfactory systems today and a neuromorphic sensor in development. Non-invasive, scalable, mail-in.

The hidden window
10–15
years of silent progression

By the time symptoms appear, the disease has already taken hold. Most of healthcare's cost arrives after diagnosis — because detection is late.

Disease-process estimate from Lewy-body / Braak staging and prodromal cohort studies (Postuma et al., Brain 2019; Berg et al., Mov Disord 2015).

The problem

Today's gold-standard tools cannot screen a population.

PET scan

$3,000–$7,000 per scan

Not scalable

Lumbar puncture

Invasive procedure

Low patient acceptance

MRI

Expensive imaging

Detects late-stage damage

Clinical symptoms

Free observation

10–15 years too late

How it works

The person emits the signal —
a trained nose reads it.

We do not test the person's own sense of smell. We detect a chemical signature the body emits — reading it with animal olfactory systems today, and a neuromorphic sensor in development, to flag potential Parkinson's (and, later, Alzheimer's) years before symptoms.

The signal
people with Parkinson's emit a disease-related volatile (VOC) signature, notably in skin sebum — captured by a simple mail-in swab.
The reader
multi-species animal olfactory detectors — dogs, rats, bees — discriminate the signature; a digital neuromorphic sensor is in development to reproduce it.
The result
a risk indication flags which people should get confirmatory neurological evaluation — years earlier, and non-invasively.

Published field evidence that the emitted signature exists and is detectable: Rooney 2025 (canine PD detection); Trivedi 2019 (VOC signature, ACS Central Science); Walton-Doyle 2025 (prodromal, npj Parkinson's Disease). See the Science page.

Our approach

Phase 1 generates revenue and validates the biology.
Phase 1 funds Phase 2.

01 Year 1 onwards · Parkinson's first

Biological screening service

Mail-in human samples, read by trained multi-species olfactory detectors — dogs, rats, and bees. Mexico-based operations, recurring revenue. Customers are pharma and CROs, clinics and hospitals, and individuals seeking early risk information — never animals or their trainers.

  • $499 single screen · $999 / $1,999 multi-screen · pharma & B2G contracts
  • 65–75% gross margin target
  • Validates the biology with paying customers
02 Year 3 to Year 10+ · adds Alzheimer's

Neuromorphic sensing + AD expansion

Bio-inspired silicon. Alzheimer's enters here as a second indication — a VOC-discovery program on the same platform. Pharma research devices, clinical sensing, per-screen licensing — the long-term moat.

  • FDA pathway via 510(k) or De Novo
  • $150K pharma device, $25K clinical sensing, $75/screen
  • Funded by Phase 1 operating profit
Why Japan

The world's most rapidly aging population already pays for annual screening.

29.4%

of Japan's population is already aged 65+ — the highest share of any major economy, projected to reach 34.8% by 2040.

¥471B

spent annually on 人間ドック (ningen dock) preventive screening — a ~$3B market with 3.7M+ voluntary participants. An entrenched behavior, not one we must create.

Sources: Japan Ministry of Internal Affairs & Communications, Sept 2025 (record 29.4% aged 65+); Japan IPSS (2040 projection). Japan Society of Ningen Dock — ~3.7M voluntary participants/year across 1,700+ certified facilities; ~¥471B (~$3B) annual market. Mandatory employer screening covers ~28M additional adults.

Most digital-health startups must teach consumers to want screening. We slot into a behavior they already have.
The team

Computational neuroscience meets animal behavior
meets digital health.

Dra. Rosalba Aguilar Velázquez

Co-Founder · CEO · Digital Health

Researcher at Universidad Veracruzana. Member of Mexico's National System of Researchers. Expertise in digital health platforms, decision-support systems, and software for neurological disorders. Published in MDPI Healthcare, Sustainability, and AppliedMath.

Dr. Pedro Paredes Ramos

Co-Founder · Animal Behavior & Detection

PhD in Neuroethology, Universidad Veracruzana. Faculty in Veterinary Medicine. Member of Mexico's National System of Researchers (Level I). Peer-reviewed publications in animal cognition, olfactory training, and behavioral protocols. Leads Mexico operations.

Jovan David Rebolledo Mendez

Co-Founder

Staff Scientist at OIST (Neural Computation Unit, Prof. Doya). Computational neuroscience and AI for neurodegenerative disease modeling. Director of Exponential Japan KK. 15+ years building Japan's innovation ecosystem. AI XPRIZE Ambassador for Japan.

Detecting neurodegeneration before it's diagnosed.

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