Technology

Two phases. One platform.

NeuroNose is built on a deliberate sequence. Phase 1 turns a proven biological capability into a revenue-generating human screening service today. Phase 2 uses that revenue to build the long-term moat: a neuromorphic sensor that reproduces the animal's olfactory detection in silicon. Each phase de-risks the next.

Phase 1 · Year 1 onwards · Parkinson's first

Biological olfactory screening service

People with Parkinson's emit a disease-related volatile (VOC) signature. Dogs, rats, and bees are documented olfactory detectors of that signature. Rather than treat this as a curiosity, NeuroNose operationalizes it: a structured, mail-in screening service for human samples, run from a low-cost operations base in Mexico. The animals are the instrument — never the customer.

  • Mail-in workflow. No clinics, no in-person visits — samples are collected and shipped, analyzed centrally, results returned digitally.
  • Trained-animal detection of the emitted human VOC signature against confirmed biomarker ground truth, with rigorous double-blind protocols modelled on the published literature.
  • Recurring revenue from subscriptions and bulk public-health contracts — not one-off transactions.
  • Each paying customer validates the biology and builds the proprietary dataset that trains Phase 2.
01
Revenue + biological validation

The mail-in workflow

1

Collect

The person being screened collects a simple, non-invasive sample using a mailed kit.

2

Ship

The sample is returned to the NeuroNose operations facility — no logistics burden on the customer.

3

Analyze

Trained-animal screening under controlled, double-blind conditions against biomarker ground truth.

4

Report

A clear, structured result is delivered digitally, with guidance on next steps.

Indicative pricing, built for scale

Lean unit economics: no clinics, Mexico-based operations, low per-test consumable cost — targeting 65–75% gross margin. B2B and B2G first.

TierPriceTarget customer
Single screen$499An individual seeking early risk information, through a clinician
3-screen subscription$999Longitudinal monitoring for at-risk individuals
5-screen subscription$1,999Extended longitudinal monitoring
ContractBulkPharma & CROs, clinics & hospitals, public-health pilots

Guardrail: animals and animal trainers are never customers — trained animals are detection instrumentation. A trainer is a customer only as an individual seeking their own result.

Phase 2 & 3 · Year 3 to Year 10+ · adds Alzheimer's

Neuromorphic olfactory sensor

The animal proves the signal is readable. The sensor makes it scalable. NeuroNose's Phase 2 is a bio-inspired silicon sensor that reproduces olfactory detection in hardware — and it is funded entirely by Phase 1 operating profit, with no sensor-only financing round required.

  • Bio-inspired architecture — neuromorphic design informed by how olfactory neural circuits actually process volatile signatures.
  • Alzheimer's enters here as a second indication — a volatile-compound discovery program on the same platform. The Alzheimer's emitted signature is not yet characterized; Parkinson's remains the lead indication.
  • FDA pathway via 510(k) or De Novo classification, with clinical validation cohorts.
  • Four revenue streams from one platform — pharma research devices, clinical screening sensors, per-screen licensing, maintenance contracts.
02
The long-term moat
Phase 2 roadmap

From prototype to FDA to commercial platform.

Year 3 – Year 6

Prototyping & R&D

Bio-inspired design and sensor prototyping. The Alzheimer's volatile-compound discovery program begins in parallel, on the same platform.

Year 6 – Year 10

FDA pathway

Regulatory route via 510(k) or De Novo classification, supported by clinical validation cohorts and dedicated regulatory affairs work.

Year 10+

Commercial launch

Pharma research devices, clinical screening sensors, and per-screen B2B licensing — a platform business, not a single product.

Why this sequencing

The biological screening service is not the consolation prize.

It is the moat — and the cash engine that builds the sensor. Most deep-tech companies must raise round after round before they have a product. NeuroNose generates revenue from year one, validates its core science with paying customers, and self-funds the hardware that becomes its long-term defensibility.

The evidence behind the platform.